Cognitive development focus on how children process information. It includes the development of knowledge, skill, and other abilities that help them to have a better understanding of the world around them. This begins from birth where the child actively learns and processes information and uses the data to develop different skills. Brain development is a part of cognitive development. Environmental toxins such as heavy metals have a deleterious effect on the human brain and nervous system.
While considering cognitive development and how it is affected by environmental toxins most studies have been conducted only on the effect of heavy metal toxins but they represent only a portion of environmental hazards. The toxins released to the environment from pollution have a damaging effect on the brain and other toxins that the highly damaging are organic chemical compounds. They are the ones that require great attention as these pass through the food chain and accumulate in animals which are then delivered to humans through different food products that we consume. The development of the brain can be affected by environmental toxins. Each toxin performs differently in the host organism. For example, Mercury has a strong potential to cause the death of the cell. Mercury can also cause alterations in the proliferation and migration of the cells. Other toxic elements such as lead can cause disruptions in neurotransmission and synaptogenesis during cell communications. Epigenomic alterations are one of the important mechanisms of toxicity in the brain development process. The methylation pattern gets altered which can also be a heritable change. The fetal brain is highly vulnerable to toxins. Exposure to toxins in children can occur in many ways. One of the common examples is the school busses, which accommodate a large number of children everyday. The exhaust from the diesel gets continuously trapped in the buses and also on the skins of the children. It is the general nature of the children to explore their surrounding environment. Sometimes they put dirt, or paints, or non-food substances into their mouth, which can also be harmful to them.
Recent studies have indicated that children with increased blood lead concentration are at the risk of reduced cognitive development and functioning resulting in lower IQ and poor academic performance. Mercury is known to cause a delay in cognitive development and is mainly associated with the consumption of fishes during pregnancy or by the child at different stages of development. This is because the fishes are known to have a significant concentration of Mercury within their bodies when water bodies are contaminated and this is then consumed by humans which causes their entry into our systems. Mercury adversely affects the development of the neurocognitive system. Lead, Mercury, and other heavy metals adversely affect brain functioning. Lead stimulate apoptosis of neurons and affects neurotransmitter release. When they are present in blood they are capable of substituting calcium which gives them access to cross the blood-brain barrier. It must be this mechanism of lead that directly affects cognitive performance. Mercury induced oxidative stress Lipid peroxidation and mitochondrial dysfunction and thus cause a decline in cognitive performance.
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