The side effects of vitamin C toxicity include diarrhea, abdominal discomfort, nausea, esophagitis, stomach ache, bloating, heartburn, and other gastric issues. Other symptoms that may occur due to a high dosage of vitamin C include headache, insomnia or feeling extremely sleepy, fatigue, and flushed skin.
Vitamin C or ascorbic acid has a very low pH that induces the stomach to release its gastric juices and pepsin. Prolonged periods of continuous release of these enzymes in the highly acidic environment cause the gastric mucosal layer to change, and hence, peptic ulcers may develop. Peptic ulcers cause heartburn, indigestion, and nausea. It is highly damaging to the walls of the stomach when vitamin C is consumed on an empty stomach. Individuals who consume 1000 mg of vitamin C may not experience any side effects since the body absorbs only 50% of the dosage, and the rest is excreted through urine.
Other complications of vitamin C toxicity
An individual consuming large doses of vitamin C either through diet or dietary supplements for a prolonged period may experience complicated symptoms of vitamin C overdose. However, these complications are not thoroughly researched. Some complications are listed below.
An individual may form kidney stones by consuming too much vitamin C. This is due to the excretion of oxalate and uric acid in the urine. These compounds may induce the formation of kidney stones.
Vitamin C overdose may interfere with the bodyâ€™s capability to absorb other nutrients. Some instances are poor absorption of vitamin B12 and copper.
Vitamin C also induces the bodyâ€™s ability to absorb iron, and as a result, an overdose may result in elevated iron levels in the body. Thus, thalassemia and hemochromatosis patients may suffer due to iron overload in their bodies.
Excessive vitamin C has shown side effects like the formation of bone spurs. However, a diet deficient in vitamin C may cause rheumatoid arthritis.
Individuals who consume vitamin C supplements along with the niacin-simvastatin drug may get diagnosed with low levels of high-density lipoprotein (HDL) cholesterol. The HDL cholesterol decreases the levels of harmful cholesterol in the blood.
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