Symptoms of Alzheimerâ€™s Disease:
Amnesia Loss of short term memory and long term memory is called amnesia. It is of two types, loss of new-recent episodes of memory and loss of memories. In this situation, the patient is unable to recognize the loved ones.
Dementia It is the most common symptom of Alzheimerâ€™s. it is a progressive form of memory loss in the elderly age of life. In later stages, it can go to advanced stages and the patient can have psychosis, hallucinations, and other psychological disorders.
Etiology Alzheimerâ€™s disease is associated with a reduction in neurotransmitters, such as acetylcholine. It is due to the lack of an enzyme known as the choline acetyltransferase. Suppose someone has one parent of Alzheimerâ€™s, then there is an increased probability of a child having the same disease. Many researchers and scientists believe that the earlier detection of the disease, the better can be the outcome with medications. It is a disease in which there is the destruction of neurons in many parts of the brain, like the cerebral hemispheres, hippocampus, and pons.
Alzheimerâ€™s and Hippocampus:
Alzheimerâ€™s affects the hippocampus and destroys it and does lead to loss of memory. As the disease gets progressive, the speech gets deteriorates. Hippocampus is connected to the mammillary body via fornix. The anterior nucleus of the thalamus is connected to the mammillary body by the mamillothalamic fibers. This pepaz circuit formation plays a crucial role in memory coding. The hippocampus helps in making the new or recent memory and loss of memory or dementia is the most common symptom of Alzheimerâ€™s.
Short Term Memory:
Short term memory is otherwise called as the recent memory. For example. Reading a topic and it is gone from our memory after a few days. This memory can be affected due to substance abuse, trauma, and excessive stress.
Treatment of Alzheimerâ€™s Disease:
Cholinesterase inhibitors help in slowing down the disease progression, along with care giving from patients relative and symptomatic drug giving are efficient ways of dealing with Alzheimerâ€™s disease.
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